Zan Mitrev clinic - Skopje



Zan Mitrev Clinic

Str. Bled Agreement No. 8

1000 Skopje



* Required


Managing Director - Academician Dr. Zan Mitrev

Dr. Zan Mitrev is a cardiovascular surgeon, founder of the first cardiosurgery in the Republic of Macedonia and the most modern hospital Zan Mitrev Clinic, founder and president of the Macedonian Society of Cardiovascular Surgery.


He was born in Stip, on January 11, 1961, and ever since he was a student in primary education he was attracted by natural sciences, and this love was strengthened during the high school education in his native town. After the graduation at the Faculty of Medicine in Skopje, he continued his education, he specialized in surgery in Zagreb, and cardiosurgery in Germany. In 2000 he performed the first bypass surgery of open heart in the Republic of Macedonia, whereby his Special Hospital for Surgical Diseases in Skopje officially started to operate.


Dr. Mitrev is internationally recognized and respected expert in the field of cardiovascular surgery with a particular interest in the surgical techniques in the field of ischemic heart disease, reconstructive valve surgery, surgery of large blood vessels, vascular surgery, as well as surgery of congenital heart defects. With more than 15.000 surgeries during his career, he is part of the group of rare cardiac surgeons in Europe. He is the only Macedonian so far, who performed the first heart transplantation in Germany in 1997.


He is a member of numerous national and international organizations, some of which include the European Board of Thoracic and Cardiovascular Surgeons, the German Society for Thoracic and Cardiovascular Surgery, the International Society for Minimally Invasive Cardiothoracic Surgery, the European Society for Artificial Organs.  


He is the winner of many prestigious awards and acknowledgments from national and international organizations, one of which is the award for best case “Coronary artery bypass grafting in awake settings”, awarded at a congress for cardiothoracic technology in Miami, Florida. He is the winner of a certificate for development of cardiosurgery in the Balkans from the board of the Balkan cardiosurgery, and for his humanity he won a statue “Mother Teresa”, the highest award for humanity in the country. The EUROPE BUSINESS ASSEMBLY and the Socrates Committee awarded Dr. Mitrev the prestigious international award “Best Health Manager and Best Hospital”.


As a recognized expert in medicine, he participates in numerous scientific and professional gatherings worldwide, and he is the organizer of numerous workshops and symposia. He has participated in dozens of scientific projects, and he has developed innovative techniques. One of them, the surgical technique of the aortic root with aortic valve replacement and related technologies, was patented in the United States in 2008.


He is the author and co-author of more than hundreds of articles and publications in the field of medicine, and he confirms his contribution in science by publishing a collection of cases from the everyday practice summarized in the book “Cardiovascular Solutions”.


Dr. Mitrev and his team are pioneers in the field of gangrene treatment, by setting a unique multi-clinical and therapeutic approach with an application of ozone therapy. He is a great humanist, supporter of sports, healthy nutrition and healthy lifestyle.




Top services from modern medicine, results based on fast and accurate diagnostics, disease prevention, execution of complex operations. Always focused on the work to expand and expand the Club of PERMANENT PATIENTS. A wide range of medical services specializing in cardiac surgery, as well as promoters of new modern services that should prevent diseases of the 21st century. Efficient and fast services available 24 hours, with the prescient diagnostics of the disease, is the motto of the team of Dr. Zan Mitrev in the shortest time frame. They are top, educated and trained professionals who respect the principles of the Code of Ethics, always ready to respond to the most complicated tasks.



We are continuously working to maintain the primacy of leaders in private health services in the region and beyond. But also to improve the level of health services and the overall healthcare system in the country. Professionalism and standardization in the work of the staff are synonymous with the working culture, which creates an institution of respect, because it is a step forward from the rest.



The patient is at the center of our attention. Diagnosis, treatment and care for him is the essence of all our activities. It continues after the patient leaves the clinic. We are building partnerships with the patients and this is our greatest benefit, which we maintain and promote in continuity, because solving health challenges is our goal.



Cardiology diagnostic and treatments

Non-invasive cardiology diagnostics

• Electrocardiogram (ECG)

• Exercise test: observing cardiac functions during exercise on a modern treadmill

• Transthoracic echocardiography (TTE): heart ultrasound with colour Doppler

• transesophageous echocardiography (TEE)

• Head, neck, arm and leg vessel ultrasound with Doppler

• Holter ECG: 24-hour ECG recording with a miniature, lightweight, modern device

• Holter for blood pressure recording blood pressure oscillations over a 24-hour period

• Cardiac pacemaker and implantable cardioverter defibrillator follow-up

• Trans telephonic 12-channel and single1-channel ECG reading in real time


Invasive cardiology diagnostics

• Heart catheterization

• Coronarography

• Electrophysiology study


Invasive cardiology treatment

• Percutaneous coronary intervention (PCI) with stent implantation

• Percutaneous intervention on peripheral arteries with stent implantation

• Percutaneous intervention on aorta with stent implantation (TEVAR)

• Heart pacemaker implantation

• Cardiac resynchronization therapy (CRT)      

• Cardioverter defibrillator implantation

• Percutaneous treatment of congenital heart defects (PFO, ASD, VSD closure etc.)


Cardiac surgery operations:

• Coronary artery bypass grafting (CABG)

• Heart valve replacement / Heart valve resonstruction

• Surgery of aorta

• Congenital heart disease surgery

• Surgery after heart and great vessels trauma

• Other heart surgery operations


Vascular surgery operations:

• Carotid artery operations

• Operations of aneurysms of the abdominal aorta

• Peripheral artery disease surgery:

  - Aortobifemoral bypass

  - Femoropopliteal bypass

  - Femorocrural bypass

• Other operations in vascular surgery


• Abdominal Surgery

Minimally aggressive - laparoscopic surgery / Classical - open abdominal surgery


• Anesthesia

Regional anesthesia / General anesthesia / Intravenous anesthesia / RIVA


• Biochemical Laboratory

Clinical biochemistry


• Hospital pharmacy


Echo examination of the abdomen / Endoscopy / Treatment of ulcer / Removal of polyps / Rectoscopy / Treatment of hemorrhoids


• Genetics and personalized medicine

Molecular diagnostics of pathogens / Nutrigenics, obesity, dieting and diabetes / Oncology and cancer therapy / Cardiovascular diseases / Pharmacogenetics / Cystic fibrosis / Personalized genetics - sequencing of a genome or exom / Non-invasive prenatal diagnosis


• Gynecology

Gynecological services


• Intensive care

Placement of intra-aortic balloon pump in patients with poor cardiac function / Intensive care / Continuous vein-venous ultrafiltration treatment in patients with acute and chronic renal failure


• Internal medicine


• Microbiology


• Neurology and Neuropsychiatry

Electroencephalography (EEG) / Evoked potentials / Auditive evoked potentials and potentials of the brainstem - BAEP / Somatosensory evoked potentials - SEP / Visible evoked potentials - VEP / Electromyography - EMG / Psychiatry


• General Surgery

Breast Surgery/ treatment of woonds


• Orthopedics

Surgery / Diagnostics


• Otorhinolaryngology

facial diagnostics with integrated HD video / Otomicroscopy / video microscopy / Audiometry, hearing examination / Tympanometry, examination of stapes reflex


• Pediatrics

Pulmo-allergogy / Pediatric Cardiology / Children's Gastro-enterology


• Psychology and psychotherapy

Psychotherapy and antistress program / Psycho-educational preparation for patients before surgery / Psychodiagnostics


• Radio Diagnostics

X-rays / 256 MSCT/ 1.5 T MRI


• Thoracic surgery

thyroid gland/ lungs


• Transfusion medicine

Transfusion of blood / Immunohematological tests / Coagulation tests (haemostasis) / Phlebological ambulance


• Urology

Diagnostics / Surgery


• Physical Therapy

KinesiTherapy / TENS therapy




Download Pricelist

Location & Contact